Gale and Ira Drukier Institute for Children's Health

Publications

2025

Gutzeit C, Grasset EK, Matthews DB, Maglione PJ, Britton GJ, Miller H, Magri G, Tomalin L, Stapylton M, Canales-Herrerias P et al..  2025.  Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses.. Sci Adv. 11(7):eado9455.
Brown JA, Bashir H, Zeng MY.  2025.  Lifelong partners: Gut microbiota-immune cell interactions from infancy to old age.. Mucosal Immunol.
Ucar D, Thibodeau A, Mejias A, Nehar-Belaid D, Marches R, Xu Z, Eryilmaz G, Josefowicz S, Paust S, Pascual V et al..  2025.  Infants display reduced NK cell responses in RSV and increased inflammatory responses in SARS-CoV-2 infections.. Res Sq.
Lucotti S, Ogitani Y, Kenific CM, Geri J, Kim YHun, Gu J, Balaji U, Bojmar L, Shaashua L, Song Y et al..  2025.  Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2.. Cell.

2024

Shailesh H, Noor S, Hayati L, Belavendra A, Van Panhuys N, Abou-Samra ABadi, Worgall S, Janahi I.  2024.  Asthma and obesity increase inflammatory markers in children.. Front Allergy. 5:1536168.
Vaquero STejedor, Neuman H, Comerma L, Marcos-Fa X, Corral-Vazquez C, Uzzan M, Pybus M, Segura-Garzón D, Guerra J, Perruzza L et al..  2024.  Immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease.. J Exp Med. 221(12)
Sloan EE, Kmetova K, NaveenKumar SK, Kluge L, Chong E, Hoy CK, Yalavarthi S, Sarosh C, Baisch J, Walters L et al..  2024.  Non-criteria antiphospholipid antibodies and calprotectin as potential biomarkers in pediatric antiphospholipid syndrome.. Clin Immunol. 261:109926.
Ravichandran S, Erra-Diaz F, Karakaslar OE, Marches R, Kenyon-Pesce L, Rossi R, Chaussabel D, Nehar-Belaid D, LaFon DC, Pascual V et al..  2024.  Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.. Nat Immunol. 25(2):316-329.
Kim Y, Maltseva N, Tesar C, Jedrzejczak R, Endres M, Ma H, Dugan HL, Stamper CT, Chang C, Li L et al..  2024.  Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.. iScience. 27(2):108976.
Menon S, Maurice D, Robinson LA, Milner J, Pascual V, Vinuesa CG, Kaicker S.  2024.  Refractory Autoimmune Thrombocytopenia in an Infant with a De Novo TLR7 Gain-of-Function Variant.. J Clin Immunol. 45(1):27.
Sanidad KZ, Rager SL, Carrow HC, Ananthanarayanan A, Callaghan R, Hart LR, Li T, Ravisankar P, Brown JA, Amir M et al..  2024.  Gut bacteria-derived serotonin promotes immune tolerance in early life.. Sci Immunol. 9(93):eadj4775.
Kim JK, Tierney BT, Overbey EG, Dantas E, Fuentealba M, Park J, S Narayanan A, Wu F, Najjar D, Chin CR et al..  2024.  Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.. Nat Commun. 15(1):4954.
Wan Z, Gu J, Balaji U, Bojmar L, Molina H, Heissel S, Pagano AE, Peralta C, Shaashua L, Ismailgeci D et al..  2024.  Optimization of ultracentrifugation-based method to enhance the purity and proteomic profiling depth of plasma-derived extracellular vesicles and particles.. J Extracell Biol. 3(7):e167.
Overbey EG, Ryon K, Kim JK, Tierney BT, Klotz R, Ortiz V, Mullane S, Schmidt JC, MacKay M, Damle N et al..  2024.  Collection of biospecimens from the inspiration4 mission establishes the standards for the space omics and medical atlas (SOMA).. Nat Commun. 15(1):4964.
Bojmar L, Kim HSang, Sugiura K, Heissel S, Lucotti S, Cioffi M, Johnson KEnnu, Cohen-Gould L, Zhang H, Molina H et al..  2024.  Protocol for cross-platform characterization of human and murine extracellular vesicles and particles.. STAR Protoc. 5(1):102754.
Overbey EG, Kim JK, Tierney BT, Park J, Houerbi N, Lucaci AG, Medina SGarcia, Damle N, Najjar D, Grigorev K et al..  2024.  The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.. Nature.
Dror S, Lucotti S, Asao T, Li J, Wortzel I, Berger LShaashua, Matei I, Boudreau N, Zhang H, Jones D et al..  2024.  Tumour-derived Extracellular Vesicle and Particle Reprogramming of Interstitial Macrophages in the Lung Pre-Metastatic Niche Enhances Vascular Permeability and Metastatic Potential.. Res Sq.
Nanaware PP, Khan ZN, Clement CC, Shetty M, Mota I, Seltzer ES, Dzieciatkowska M, Gamboni F, D'Alessandro A, Ng C et al..  2024.  Role of the afferent lymph as an immunological conduit to analyze tissue antigenic and inflammatory load.. Cell Rep. 43(6):114311.
Balaji U, Rodriguez-Alcazar J, Balasubramanian P, Smitherman C, Baisch J, Pascual V, Gu J.  2024.  Ragas: integration and enhanced visualization for single cell subcluster analysis.. Bioinformatics. 40(6)
Caielli S, Balasubramanian P, Rodriguez-Alcazar J, Balaji U, Robinson L, Wan Z, Baisch J, Smitherman C, Walters L, Sparagana P et al..  2024.  Type I IFN drives unconventional IL-1β secretion in lupus monocytes.. Immunity.
Wortzel I, Seo Y, Akano I, Shaashua L, Tobias GCardial, Hebert J, Kim K-A, Kim DA, Dror S, Liu Y et al..  2024.  Unique structural configuration of EV-DNA primes Kupffer cell-mediated antitumor immunity to prevent metastatic progression.. Nat Cancer.
Searles SC, Chen W-S, Yee JD, Lee P, Lee CK, Caron C, Neto F, Matei I, Lyden D, Bui JD.  2024.  MAP kinase kinase 1 (MEK1) within extracellular vesicles inhibits tumour growth by promoting anti-tumour immunity.. J Extracell Vesicles. 13(10):e12515.
Garagozlo K, Han J-Y, Worgall S, Thomas C, Wu A, Chang N, Gerber LM, Fiorino EK.  2024.  Validation of diagnostic coding for children's interstitial lung disease (chILD).. Pediatr Pulmonol. 59(2):521-525.

2023

Antonisamy B, Shailesh H, Hani Y, Ahmed LHayati M, Noor S, Ahmed SYahya, Alfaki M, Muhayimana A, Jacob SSunny, Balayya SKotegar et al..  2023.  Sphingolipids in Childhood Asthma and Obesity (SOAP Study): A Protocol of a Cross-Sectional Study.. Metabolites. 13(11)
Kusakabe T, Lin W-Y, Cheong J-G, Singh G, Ravishankar A, Yeung ST, Mesko M, DeCelie MBialt, Carriche G, Zhao Z et al..  2023.  Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19.. Nat Immunol. 24(11):1879-1889.
Cheong J-G, Ravishankar A, Sharma S, Parkhurst CN, Grassmann SA, Wingert CK, Laurent P, Ma S, Paddock L, Miranda IC et al..  2023.  Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.. Cell. 186(18):3882-3902.e24.
Caielli S, Balasubramanian P, Rodriguez-Alcazar J, Balaji U, Wan Z, Baisch J, Smitherman C, Walters L, Sparagana P, Nehar-Belaid D et al..  2023.  An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes.. bioRxiv.
Nouri N, Cao RGiacomelli, Bunsow E, Nehar-Belaid D, Marches R, Xu Z, Smith B, Heinonen S, Mertz S, Leber A et al..  2023.  Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations.. Nat Commun. 14(1):7976.
Kudo T, Zhao ML, Jeknić S, Kovary KM, LaGory EL, Covert MW, Teruel MN.  2023.  Context-dependent regulation of lipid accumulation in adipocytes by a HIF1α-PPARγ feedback network.. Cell Syst. 14(12):1074-1086.e7.
Gofshteyn J, Mansfield L, Spitznagle J, Balasubramanian P, Cardenas J, Miller T, Gu J, Wang X, Punaro M, Fuller J et al..  2023.  Juvenile dermatomyositis disease activity is associated with the expansion of blood B and T-cell memory subsets lacking follicular markers.. Arthritis Rheumatol.
Ravichandran S, Erra-Diaz F, Karakaslar OE, Marches R, Kenyon-Pesce L, Rossi R, Chaussabel D, Pascual V, Palucka K, Paust S et al..  2023.  Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults.. medRxiv.
Cumpelik A, Cody E, Yu SMon-Wei, Grasset EK, Dominguez-Sola D, Cerutti A, Heeger PS.  2023.  Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice.. J Immunol. 210(1):19-23.
Lengel HB, Mastrogiacomo B, Connolly JG, Tan KSee, Liu Y, Fick CN, Dunne EG, He D, Lankadasari MB, Satravada BAnusha et al..  2023.  Genomic mapping of metastatic organotropism in lung adenocarcinoma.. Cancer Cell. 41(5):970-985.e3.
Liu S, Benito-Martin A, Vatter FAPelissie, Hanif SZ, Liu C, Bhardwaj P, Sethupathy P, Farghli AR, Piloco P, Paik P et al..  2023.  Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism.. bioRxiv.
Rager SL, Zeng MY.  2023.  The Gut-Liver Axis in Pediatric Liver Health and Disease.. Microorganisms. 11(3)
Yu S, Zeng MY.  2023.  Sex-biased gut dopamine signaling in multiple sclerosis.. Immunity. 56(12):2674-2676.
Kenari ANasiri, Bojmar L, Heissel S, Molina H, Lyden D, Hoshino A.  2023.  Protocol for Plasma Extracellular Vesicle and Particle Isolation and Mass Spectrometry-Based Proteomic Identification.. Methods Mol Biol. 2628:291-300.
Borowska MT, Boughter CT, Bunker JJ, Guthmiller JJ, Wilson PC, Roux B, Bendelac A, Adams EJ.  2023.  Biochemical and biophysical characterization of natural polyreactivity in antibodies.. Cell Rep. 42(10):113190.
Caielli S, Wan Z, Pascual V.  2023.  Systemic Lupus Erythematosus Pathogenesis: Interferon and Beyond.. Annu Rev Immunol.
Borowska MT, Boughter CT, Bunker JJ, Guthmiller JJ, Wilson PC, Roux B, Bendelac A, Adams EJ.  2023.  Biochemical and biophysical characterization of natural polyreactivity in antibodies.. Cell Rep. 42(10):113190.
Liu S, Benito-Martin A, Vatter FAPelissie, Hanif SZ, Liu C, Bhardwaj P, Sethupathy P, Farghli AR, Piloco P, Paik P et al..  2023.  Breast adipose tissue-derived extracellular vesicles from obese women alter tumor cell metabolism.. EMBO Rep. 24(12):e57339.
Changrob S, Halfmann PJ, Liu H, Torres JL, McGrath JJC, Ozorowski G, Li L, G Wilbanks D, Kuroda M, Maemura T et al..  2023.  Site of vulnerability on SARS-CoV-2 spike induces broadly protective antibody to antigenically distinct Omicron subvariants.. J Clin Invest.
Bolton MJ, Santos JJS, Arevalo CP, Griesman T, Watson M, Li SHang, Bates P, Ramage H, Wilson PC, Hensley SE.  2023.  IgG3 subclass antibodies recognize antigenically drifted influenza viruses and SARS-CoV-2 variants through efficient bivalent binding.. Proc Natl Acad Sci U S A. 120(35):e2216521120.
Uryu K, Soplop N, Sheahan TP, Catanese M-T, Huynh C, Pena J, Boudreau N, Matei I, Kenific C, Hashimoto A et al..  2023.  Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach.. bioRxiv.
Worgall S.  2023.  Environmental exposures: another effect on sphingolipids in asthma? Thorax. 78(3):222.
Vieira MC, Palm A-KE, Stamper CT, Tepora ME, Nguyen KD, Pham TD, Boyd SD, Wilson PC, Cobey S.  2023.  Germline-encoded specificities and the predictability of the B cell response.. PLoS Pathog. 19(8):e1011603.
Gregucci F, Spada S, Barcellos-Hoff MHelen, Bhardwaj N, Hak CChan Wah, Fiorentino A, Guha C, Guzman ML, Harrington K, Herrera FG et al..  2023.  Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference.. Oncoimmunology. 12(1):2222560.
Asao T, Tobias GCardial, Lucotti S, Jones DR, Matei I, Lyden D.  2023.  Extracellular vesicles and particles as mediators of long-range communication in cancer: connecting biological function to clinical applications.. Extracell Vesicles Circ Nucl Acids. 4(3):461-485.
Savage A, Risquez C, Gomi K, Schreiner R, Borczuk AC, Worgall S, Silver RB.  2023.  The mast cell exosome-fibroblast connection: A novel pro-fibrotic pathway.. Front Med (Lausanne). 10:1139397.
Shaw DG, Aguirre-Gamboa R, Vieira MC, Gona S, DiNardi N, Wang A, Dumaine A, Gelderloos-Arends J, Earley ZM, Meckel KR et al..  2023.  Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis.. Nat Med. 29(6):1520-1529.
Wang G, Li J, Bojmar L, Chen H, Li Z, Tobias GC, Hu M, Homan EA, Lucotti S, Zhao F et al..  2023.  Tumour extracellular vesicles and particles induce liver metabolic dysfunction.. Nature. 618(7964):374-382.
Dyke JP, Voskrebenzev A, Blatt LK, Vogel-Claussen J, Grimm R, Worgall S, Perlman JM, Kovanlikaya A.  2023.  Assessment of lung ventilation of premature infants with bronchopulmonary dysplasia at 1.5 Tesla using phase-resolved functional lung magnetic resonance imaging.. Pediatr Radiol.
Li L, Sun J, Fu Y, Changrob S, McGrath JJC, Wilson PC.  2023.  A hybrid single cell demultiplexing strategy that increases both cell recovery rate and calling accuracy.. bioRxiv.
Hu M, Kenific CM, Boudreau N, Lyden D.  2023.  Tumor-derived nanoseeds condition the soil for metastatic organotropism.. Semin Cancer Biol. 93:70-82.
McGrath JJC, Wilson PC.  2023.  Fate-mapping antibodies to study sinful immune dynamics.. Nat Immunol. 24(4):570-572.
Blavier L, Nakata R, Neviani P, Sharma K, Shimada H, Benedicto A, Matei I, Lyden D, DeClerck YA.  2023.  The capture of extracellular vesicles endogenously released by xenotransplanted tumours induces an inflammatory reaction in the premetastatic niche.. J Extracell Vesicles. 12(5):e12326.

2022

Choi J, Cho HYeon, Jeon J, Kim K-A, Han YDae, Ahn JBae, Wortzel I, Lyden D, Kim HSang.  2022.  Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer.. Front Oncol. 12:1067210.
Dai J, Cimino PJ, Gouin KH, Grzelak CA, Barrett A, Lim AR, Long A, Weaver S, Saldin LT, Uzamere A et al..  2022.  Astrocytic laminin-211 drives disseminated breast tumor cell dormancy in brain.. Nat Cancer. 3(1):25-42.
Yu F, Courjaret R, Elmi A, Adap EAlcantara, Orie NN, Zghyer F, Hubrack S, Hayat S, Asaad N, Worgall S et al..  2022.  Chronic reduction of store operated Ca2+ entry is viable therapeutically but is associated with cardiovascular complications.. J Physiol. 600(22):4827-4848.
Zhang Z-B, Sinha J, Bahrami-Nejad Z, Teruel MN.  2022.  The circadian clock mediates daily bursts of cell differentiation by periodically restricting cell-differentiation commitment.. Proc Natl Acad Sci U S A. 119(33):e2204470119.
Bolton MJ, Arevalo CP, Griesman T, Li SHang, Bates P, Wilson PC, Hensley SE.  2022.  IgG3 subclass antibodies recognize antigenically drifted influenza viruses and SARS-CoV-2 variants through efficient bivalent binding.. bioRxiv.
Shaashua L, Ben-Shmuel A, Pevsner-Fischer M, Friedman G, Levi-Galibov O, Nandakumar S, Barki D, Nevo R, Brown LE, Zhang W et al..  2022.  BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling.. Nat Commun. 13(1):6513.
Gourari I, Gomi R, Young M, Jordan G, Liongson M, Heras A, Gerber LM, Thomas C, Tsirilakis K, Ono J et al..  2022.  Asthma 17q21 polymorphism associates with decreased risk of COVID-19 in children.. Pediatr Pulmonol. 57(11):2855-2860.
Tholen S, Patel R, Agas A, Kovary KM, Rabiee A, Nicholls HT, Bielczyk-Maczyńska E, Yang W, Kraemer FB, Teruel MN.  2022.  Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy.. Cell Rep. 39(13):111018.
Sant AJ, Wilson PC.  2022.  Learning from our differences.. Nat Immunol. 23(10):1403-1404.
Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Ganesh KShobana, Cho S, Endress J, Schild T et al..  2022.  Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.. Nat Commun. 13(1):6239.
Jin JC, Ananthanarayanan A, Brown JA, Rager SL, Bram Y, Sanidad KZ, Amir M, Baergen RN, Stuhlmann H, Schwartz RE et al..  2022.  SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy.. Pediatr Res. :1-8.
Li L, Lan LYu-Ling, Huang L, Ye C, Andrade J, Wilson PC.  2022.  Selecting Representative Samples From Complex Biological Datasets Using K-Medoids Clustering.. Front Genet. 13:954024.
Grasset EK, Alenghat T.  2022.  Good intentions gone wrong: The B cell block to epithelial repair.. Immunity. 55(12):2222-2224.
Strillacci A, Sansone P, Rajasekhar VK, Turkekul M, Boyko V, Meng F, Houck-Loomis B, Brown D, Berger MF, Hendrickson RC et al..  2022.  ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance.. NPJ Breast Cancer. 8(1):96.
Lucotti S, Kenific CM, Zhang H, Lyden D.  2022.  Extracellular vesicles and particles impact the systemic landscape of cancer.. EMBO J. 41(18):e109288.
McGrath JJC, Li L, Wilson PC.  2022.  Memory B cell diversity: insights for optimized vaccine design.. Trends Immunol. 43(5):343-354.
Li L, Changrob S, Fu Y, Stovicek O, Guthmiller JJ, McGrath JJC, Dugan HL, Stamper CT, Zheng N-Y, Huang M et al..  2022.  Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens.. Brief Bioinform. 23(2)
Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P et al..  2022.  mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.. Nat Commun. 13(1):6915.
Brown GJ, Canete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI et al..  2022.  TLR7 gain-of-function genetic variation causes human lupus.. Nature.
Wasserman E, Gomi R, Sharma A, Hong S, Bareja R, Gu J, Balaji U, Veerappan A, Kim BI, Wu W et al..  2022.  Human Rhinovirus Infection of the Respiratory Tract Affects Sphingolipid Synthesis.. Am J Respir Cell Mol Biol. 66(3):302-311.
Sanidad KZ, Amir M, Ananthanarayanan A, Singaraju A, Shiland NB, Hong HS, Kamada N, Inohara N, Nunez G, Zeng MY.  2022.  Maternal gut microbiome-induced IgG regulates neonatal gut microbiome and immunity.. Sci Immunol. 7(72):eabh3816.
Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M et al..  2022.  Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection.. Gut Microbes. 14(1):2105609.
Lyden D, Ghajar CM, Correia ALuísa, Aguirre-Ghiso JA, Cai S, Rescigno M, Zhang P, Hu G, Fendt S-M, Boire A et al..  2022.  Metastasis.. Cancer Cell. 40(8):787-791.
Khan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.  2022.  Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems.. Clin Exp Metastasis.
Heras A, Gomi R, Young M, Chang CL, Wasserman E, Sharma A, Wu W, Gu J, Balaji U, White R et al..  2022.  Dietary long-chain omega 3 fatty acids modify sphingolipid metabolism to facilitate airway hyperreactivity.. Sci Rep. 12(1):19735.
Bahrami-Nejad Z, Zhang Z-B, Tholen S, Sharma S, Rabiee A, Zhao ML, Kraemer FB, Teruel MN.  2022.  Early enforcement of cell identity by a functional component of the terminally differentiated state.. PLoS Biol. 20(12):e3001900.
Arifuzzaman M, Won THyung, Li T-T, Yano H, Digumarthi S, Heras AF, Zhang W, Parkhurst CN, Kashyap S, Jin W-B et al..  2022.  Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.. Nature. 611(7936):578-584.
Ortiz R, Kluwe B, Lazarus S, Teruel MN, Joseph JJ.  2022.  Cortisol and cardiometabolic disease: a target for advancing health equity.. Trends Endocrinol Metab. 33(11):786-797.
Briquez PS, Rouhani SJ, Yu J, Pyzer AR, Trujillo J, Dugan HL, Stamper CT, Changrob S, Sperling AI, Wilson PC et al..  2022.  Severe COVID-19 induces autoantibodies against angiotensin II that correlate with blood pressure dysregulation and disease severity.. Sci Adv. 8(40):eabn3777.

2021

Shor RE, Dai J, Lee S-Y, Pisarsky L, Matei I, Lucotti S, Lyden D, Bissell MJ, Ghajar CM.  2021.  The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings.. Mol Oncol.
Wang G, Zhang H, Lyden D.  2021.  Tumour-regulated anorexia preceding cachexia.. Nat Cell Biol. 23(2):111-113.
García-Silva S, Benito-Martin A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AAmor et al..  2021.  Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism.. Nat Cancer. 2(12):1387-1405.
Grunberg N, Pevsner-Fischer M, Goshen-Lago T, Diment J, Stein Y, Lavon H, Mayer S, Levi-Galibov O, Friedman G, Ofir-Birin Y et al..  2021.  Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.. Cancer Res. 81(7):1639-1653.
Vatter FAPelissie, Cioffi M, Hanna SJ, Castarede I, Caielli S, Pascual V, Matei I, Lyden D.  2021.  Extracellular vesicle- and particle-mediated communication shapes innate and adaptive immune responses.. J Exp Med. 218(8)
Altman MC, Rinchai D, Baldwin N, Toufiq M, Whalen E, Garand M, Kabeer BSyed Ahame, Alfaki M, Presnell SR, Khaenam P et al..  2021.  Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.. Nat Commun. 12(1):4385.
Li L, Dugan HL, Stamper CT, Lan LYu-Ling, Asby NW, Knight M, Stovicek O, Zheng N-Y, Madariaga MLucia, Shanmugarajah K et al..  2021.  Improved integration of single-cell transcriptome and surface protein expression by LinQ-View.. Cell Rep Methods. 1(4):100056.
Jones GD, Brandt WS, Shen R, Sanchez-Vega F, Tan KSee, Martin A, Zhou J, Berger M, Solit DB, Schultz N et al..  2021.  A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.. JAMA Surg. 156(2):e205601.
Kenific CM, Zhang H, Lyden D.  2021.  An exosome pathway without an ESCRT.. Cell Res. 31(2):105-106.
Amir M, Zeng MY.  2021.  Immune imprinting in utero.. Science. 373(6558):967-968.
Wan Z, Pascual V.  2021.  Breaching self-tolerance by targeting the gatekeeper.. J Exp Med. 218(5)
Wasserman E, Worgall S.  2021.  Perinatal origins of chronic lung disease: mechanisms-prevention-therapy-sphingolipid metabolism and the genetic and perinatal origins of childhood asthma.. Mol Cell Pediatr. 8(1):22.
Lawlor N, Nehar-Belaid D, Grassmann JDS, Stoeckius M, Smibert P, Stitzel ML, Pascual V, Banchereau J, Williams A, Ucar D.  2021.  Single Cell Analysis of Blood Mononuclear Cells Stimulated Through Either LPS or Anti-CD3 and Anti-CD28.. Front Immunol. 12:636720.
Cullen SM, Hassan N, Smith-Raska M.  2021.  Effects of non-inherited ancestral genotypes on offspring phenotypes.. Biol Reprod.
Bojmar L, Kim HSang, Tobias GC, Vatter FAPelissie, Lucotti S, Gyan KEnnu, Kenific CM, Wan Z, Kim K-A, Kim DA et al..  2021.  Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids.. STAR Protoc. 2(1):100225.
Teng F, Tachó-Piñot R, Sung B, Farber DL, Worgall S, Hammad H, Lambrecht BN, Hepworth MR, Sonnenberg GF.  2021.  ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.. Cell Rep. 37(8):110051.
Tycko J, Adam VS, Crosariol M, Ohlstein J, Sanmiguel J, Tretiakova AP, Roy S, Worgall S, Wilson JM, Limberis MP.  2021.  Adeno-Associated Virus Vector-Mediated Expression of Antirespiratory Syncytial Virus Antibody Prevents Infection in Mouse Airways.. Hum Gene Ther.
Ono JG, Worgall S.  2021.  More Evidence for Inborn Dysregulation of Sphingolipid Metabolism in Children with Asthma? Am J Respir Crit Care Med. 203(7):792-793.
Caielli S, Cardenas J, de Jesus AAlmeida, Baisch J, Walters L, Blanck JPhilippe, Balasubramanian P, Stagnar C, Ohouo M, Hong S et al..  2021.  Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE.. Cell.
Winkler A, Sun W, De S, Jiao A, M Sharif N, Symanowicz PT, Athale S, Shin JH, Wang J, Jacobson BA et al..  2021.  The IRAK4 kinase inhibitor PF-06650833 blocks inflammation in preclinical models of rheumatologic disease and in humans enrolled in a randomized clinical trial.. Arthritis Rheumatol.
Notaras M, Lodhi A, Barrio-Alonso E, Foord C, Rodrick T, Jones D, Fang H, Greening D, Colak D.  2021.  Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids.. Mol Psychiatry.
Jones GD, Caso R, Tan KSee, Mastrogiacomo B, Sanchez-Vega F, Liu Y, Connolly JG, Murciano-Goroff YR, Bott MJ, Adusumilli PS et al..  2021.  KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma.. Clin Cancer Res. 27(9):2604-2612.
Guthmiller JJ, Han J, Utset HA, Li L, Lan LYu-Ling, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML et al..  2021.  Broadly neutralizing antibodies target a hemagglutinin anchor epitope.. Nature.
Norgard RJ, Pitarresi JR, Maddipati R, Aiello-Couzo NM, Balli D, Li J, Yamazoe T, Wengyn MD, Millstein ID, Folkert IW et al..  2021.  Calcium signaling induces a partial EMT.. EMBO Rep. :e51872.
Doron I, Mesko M, Li XV, Kusakabe T, Leonardi I, Shaw DG, Fiers WD, Lin W-Y, Bialt-DeCelie M, Román E et al..  2021.  Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn's disease.. Nat Microbiol. 6(12):1493-1504.

2020

James JA, Guthridge JM, Chen H, Lu R, Bourn RL, Bean K, Munroe ME, Smith M, Chakravarty E, Baer AN et al..  2020.  Unique Sjögren's syndrome patient subsets defined by molecular features.. Rheumatology (Oxford). 59(4):860-868.
Hoshino A, Kim HSang, Bojmar L, Gyan KEnnu, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S et al..  2020.  Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.. Cell. 182(4):1044-1061.e18.
Nehar-Belaid D, Hong S, Marches R, Chen G, Bolisetty M, Baisch J, Walters L, Punaro M, Rossi RJ, Chung C-H et al..  2020.  Mapping systemic lupus erythematosus heterogeneity at the single-cell level.. Nat Immunol.
Zimmer AS, Steinberg SM, Smart DDee, Gilbert MR, Armstrong TS, Burton E, Houston N, Biassou N, Gril B, Brastianos PK et al..  2020.  Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.. Future Oncol. 16(14):899-909.
Zhao ML, Rabiee A, Kovary KM, Bahrami-Nejad Z, Taylor B, Teruel MN.  2020.  Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle.. Cell Rep. 31(11):107769.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F et al..  2020.  A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.. Cell Stem Cell. 27(1):125-136.e7.
Bezdan D, Grigorev K, Meydan C, Vatter FAPelissie, Cioffi M, Rao V, MacKay M, Nakahira K, Burnham P, Afshinnekoo E et al..  2020.  Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.. iScience. 23(12):101844.
Heras AF, Veerappan A, Silver RB, Emala CW, Worgall TS, Perez-Zoghbi J, Worgall S.  2020.  Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity.. Am J Respir Cell Mol Biol.
Ono JG, Kim BI, Zhao Y, Christos PJ, Tesfaigzi Y, Worgall TS, Worgall S.  2020.  Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes.. J Clin Invest. 130(2):921-926.
Sanidad KZ, Zeng MY.  2020.  Neonatal gut microbiome and immunity.. Curr Opin Microbiol. 56:30-37.
Amir M, Brown JA, Rager SL, Sanidad KZ, Ananthanarayanan A, Zeng MY.  2020.  Maternal Microbiome and Infections in Pregnancy.. Microorganisms. 8(12)
Senaldi L, Smith-Raska M.  2020.  Evidence for germline non-genetic inheritance of human phenotypes and diseases.. Clin Epigenetics. 12(1):136.
Subrahmanyam PB, Holmes TH, Lin D, Su LF, Obermoser G, Banchereau J, Pascual V, García-Sastre A, Albrecht RA, Palucka K et al..  2020.  Mass Cytometry Defines Virus-Specific CD4 T Cells in Influenza Vaccination.. Immunohorizons. 4(12):774-788.
Sanidad KZ, Zeng MY.  2020.  LOS in The Dysbiotic Gut.. Cell Host Microbe. 27(1):11-13.
Martinez OM, Bridges ND, Goldmuntz E, Pascual V.  2020.  The immune roadmap for understanding multi-system inflammatory syndrome in children: opportunities and challenges.. Nat Med. 26(12):1819-1824.
Sondhi D, Kaminsky SM, Hackett NR, Pagovich OE, Rosenberg JB, De BP, Chen A, Van de Graaf B, Mezey JG, Mammen GW et al..  2020.  Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.. Sci Transl Med. 12(572)

2019

Gupta MP, Tandalam S, Ostrager S, Lever AS, Fung AR, Hurley DD, Alegre GB, Espinal JE, H Remmel L, Mukherjee S et al..  2019.  Non-reversible tissue fixation retains extracellular vesicles for in situ imaging.. Nat Methods. 16(12):1269-1273.
Notaras M, Allen M, Longo F, Volk N, Toth M, Jeon NLi, Klann E, Colak D.  2019.  UPF2 leads to degradation of dendritically targeted mRNAs to regulate synaptic plasticity and cognitive function.. Mol Psychiatry.
Rodrigues G, Hoshino A, Kenific CM, Matei IR, Steiner L, Freitas D, Kim HSang, Oxley PR, Scandariato I, Casanova-Salas I et al..  2019.  Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis.. Nat Cell Biol. 21(11):1403-1412.
Rodrigues G, Zhang H, Lyden DC.  2019.  Tumour vesicular micromachinery uncovered.. Nat Cell Biol. 21(7):795-797.
Stowers RS, Shcherbina A, Israeli J, Gruber JJ, Chang J, Nam S, Rabiee A, Teruel MN, Snyder MP, Kundaje A et al..  2019.  Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility.. Nat Biomed Eng. 3(12):1009-1019.
Prakash V, Carson BB, Feenstra JM, Dass RA, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks MM, Kurylo CM et al..  2019.  Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease.. Nat Commun. 10(1):2110.
Wortzel I, Dror S, Kenific CM, Lyden DC.  2019.  Exosome-Mediated Metastasis: Communication from a Distance.. Dev Cell. 49(3):347-360.
Zhang H, Lyden DC.  2019.  Asymmetric-flow field-flow fractionation technology for exomere and small extracellular vesicle separation and characterization.. Nat Protoc. 14(4):1027-1053.
Kenific CM, Wang G, Lyden DC.  2019.  Tumor Extracellular Vesicles Impede Interferon Alert Responses.. Cancer Cell. 35(1):3-5.
Zeng MY, Miralda I, Armstrong CL, Uriarte SM, Bagaitkar J.  2019.  The roles of NADPH oxidase in modulating neutrophil effector responses.. Mol Oral Microbiol. 34(2):27-38.
Ramakrishnan SK, Zhang H, Ma X, Jung I, Schwartz AJ, Triner D, Devenport SN, Das NK, Xue X, Zeng MY et al..  2019.  Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.. Nat Commun. 10(1):660.
Caielli S, Veiga DTroggian, Balasubramanian P, Athale S, Domic B, Murat E, Banchereau R, Xu Z, Chandra M, Chung C-H et al..  2019.  A CD4 T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate.. Nat Med. 25(1):75-81.
Caballero-Flores G, Sakamoto K, Zeng MY, Wang Y, Hakim J, Matus-Acuña V, Inohara N, Nunez G.  2019.  Maternal Immunization Confers Protection to the Offspring against an Attaching and Effacing Pathogen through Delivery of IgG in Breast Milk.. Cell Host Microbe. 25(2):313-323.e4.
Hong S, Banchereau R, Maslow B-SL, Guerra MM, Cardenas J, Baisch J, D Branch W, T Porter F, Sawitzke A, Laskin CA et al..  2019.  Longitudinal profiling of human blood transcriptome in healthy and lupus pregnancy.. J Exp Med. 216(5):1154-1169.
Jiang SH, Athanasopoulos V, Ellyard JI, Chuah A, Cappello J, Cook A, Prabhu SB, Cardenas J, Gu J, Stanley M et al..  2019.  Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus.. Nat Commun. 10(1):2201.
Assassi S, Wang X, Chen G, Goldmuntz E, Keyes-Elstein L, Ying J, Wallace PK, Turner J, W Zheng J, Pascual V et al..  2019.  Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.. Ann Rheum Dis. 78(10):1371-1378.

2018

Gomi R, Sharma A, Wu W, Worgall S.  2018.  Neonatal Genetic Delivery of Anti-Respiratory Syncytial Virus (RSV) Antibody by Non-Human Primate-Based Adenoviral Vector to Provide Protection against RSV.. Vaccines (Basel). 7(1)
Kovary KM, Taylor B, Zhao ML, Teruel MN.  2018.  Expression variation and covariation impair analog and enable binary signaling control.. Mol Syst Biol. 14(5):e7997.
Bahrami-Nejad Z, Zhao ML, Tholen S, Hunerdosse D, Tkach KE, van Schie S, Chung M, Teruel MN.  2018.  A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation.. Cell Metab. 27(4):854-868.e8.
Matei IR, Rampersaud S, Lyden DC.  2018.  Engineered niches model the onset of metastasis.. Nat Biomed Eng. 2(12):885-887.
Wittkowski KM, Dadurian C, Seybold MP, Kim HSang, Hoshino A, Lyden DC.  2018.  Complex polymorphisms in endocytosis genes suggest alpha-cyclodextrin as a treatment for breast cancer.. PLoS One. 13(7):e0199012.
Jaggi P, Mejias A, Xu Z, Yin H, Moore-Clingenpeel M, Smith B, Burns JC, Tremoulet AH, Jordan-Villegas A, Chaussabel D et al..  2018.  Whole blood transcriptional profiles as a prognostic tool in complete and incomplete Kawasaki Disease.. PLoS One. 13(5):e0197858.
Zheng J, Hernandez JM, Doussot A, Bojmar L, Zambirinis CP, Costa-Silva B, van Beek EJAH, Mark MTesic, Molina H, Askan G et al..  2018.  Extracellular matrix proteins and carcinoembryonic antigen-related cell adhesion molecules characterize pancreatic duct fluid exosomes in patients with pancreatic cancer.. HPB (Oxford). 20(7):597-604.
Zhang Y, Gupta S, Ilstad-Minnihan A, Ayyangar S, Hay AD, Pascual V, Ilowite NT, Macaubas C, Mellins ED.  2018.  Interleukin-1 in monocyte activation phenotypes in systemic juvenile idiopathic arthritis: Observations from a clinical trial of rilonacept, an interleukin-1 inhibitor.. Clin Immunol. 194:9-18.
Zhang H, Freitas D, Kim HSang, Fabijanic K, Li Z, Chen H, Mark MTesic, Molina H, Martin ABenito, Bojmar L et al..  2018.  Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation.. Nat Cell Biol. 20(3):332-343.
Wu T-C, Xu K, Martinek J, Young RR, Banchereau R, George J, Turner J, Kim KIn, Zurawski S, Wang X et al..  2018.  IL1 Receptor Antagonist Controls Transcriptional Signature of Inflammation in Patients with Metastatic Breast Cancer.. Cancer Res. 78(18):5243-5258.
Parks MM, Kurylo CM, Dass RA, Bojmar L, Lyden DC, C Vincent T, Blanchard SC.  2018.  Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression.. Sci Adv. 4(2):eaao0665.
Jacquemin C, Augusto J-F, Scherlinger M, Gensous N, Forcade E, Douchet I, Levionnois E, Richez C, Lazaro E, Duffau P et al..  2018.  OX40L/OX40 axis impairs follicular and natural Treg function in human SLE.. JCI Insight. 3(24)
Kramer K, Pandit-Taskar N, Humm JL, Zanzonico PB, Haque S, Dunkel IJ, Wolden SL, Donzelli M, Goldman DA, Lewis JS et al..  2018.  A phase II study of radioimmunotherapy with intraventricular I-3F8 for medulloblastoma.. Pediatr Blood Cancer. 65(1)
Zarnegar S, Durham BH, Khattar P, Shukla NN, Benayed R, Lacouture ME, Lavi E, Lyden DC, Diamond EL, Dunkel IJ et al..  2018.  Novel activating BRAF fusion identifies a recurrent alternative mechanism for ERK activation in pediatric Langerhans cell histiocytosis.. Pediatr Blood Cancer. 65(1)
Bagaitkar J, Huang J, Zeng MY, Pech NK, Monlish DA, Perez-Zapata LJ, Miralda I, Schuettpelz LG, Dinauer MC.  2018.  NADPH oxidase activation regulates apoptotic neutrophil clearance by murine macrophages.. Blood. 131(21):2367-2378.
Burg N, Swendeman S, Worgall S, Hla T, Salmon JE.  2018.  Sphingosine 1-Phosphate Receptor 1 Signaling Maintains Endothelial Cell Barrier Function and Protects Against Immune Complex-Induced Vascular Injury.. Arthritis Rheumatol. 70(11):1879-1889.
Worgall S.  2018.  Stranger in a Strange Land: IL-8 in the Mouse Lung? Am J Respir Cell Mol Biol. 59(5):525-526.

2017

Kim D, Seo S-U, Zeng MY, Kim W-U, Kamada N, Inohara N, Nunez G.  2017.  Mesenchymal Cell-Specific MyD88 Signaling Promotes Systemic Dissemination of via Inflammatory Monocytes.. J Immunol. 199(4):1362-1371.
Matei IR, Kim HSang, Lyden DC.  2017.  Unshielding Exosomal RNA Unleashes Tumor Growth And Metastasis.. Cell. 170(2):223-225.
Zeng MY, Inohara N, Nuñez G.  2017.  Mechanisms of inflammation-driven bacterial dysbiosis in the gut.. Mucosal Immunol. 10(1):18-26.
Becher OJ, Gilheeney SW, Khakoo Y, Lyden DC, Haque S, De Braganca KC, Kolesar JM, Huse JT, Modak S, Wexler LH et al..  2017.  A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.. Pediatr Blood Cancer. 64(7)
Jourde-Chiche N, Whalen E, Gondouin B, Speake C, Gersuk V, Dussol B, Burtey S, Pascual V, Chaussabel D, Chiche L.  2017.  Modular transcriptional repertoire analyses identify a blood neutrophil signature as a candidate biomarker for lupus nephritis.. Rheumatology (Oxford). 56(3):477-487.
Rajappa P, Cobb WS, Vartanian E, Huang Y, Daly LA, Hoffman C, Zhang J, Shen B, Yanowitch R, Garg K et al..  2017.  Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells.. Clin Cancer Res. 23(12):3109-3119.
Athale S, Banchereau R, Thompson-Snipes LA, Wang Y, Palucka K, Pascual V, Banchereau J.  2017.  Influenza vaccines differentially regulate the interferon response in human dendritic cell subsets.. Sci Transl Med. 9(382)
Becher OJ, Millard NE, Modak S, Kushner BH, Haque S, Spasojevic I, Trippett TM, Gilheeney SW, Khakoo Y, Lyden DC et al..  2017.  A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors.. PLoS One. 12(6):e0178593.
Arostegui JI, Anton J, Calvo I, Robles A, Iglesias E, López-Montesinos B, Banchereau R, Hong S, Joubert Y, Junge G et al..  2017.  Open-Label, Phase II Study to Assess the Efficacy and Safety of Canakinumab Treatment in Active Hyperimmunoglobulinemia D With Periodic Fever Syndrome.. Arthritis Rheumatol. 69(8):1679-1688.
Hoshino A, Lyden DC.  2017.  Metastasis: Lymphatic detours for cancer.. Nature. 546(7660):609-610.
Silvin A, Yu CI, Lahaye X, Imperatore F, Brault J-B, Cardinaud S, Becker C, Kwan W-H, Conrad C, Maurin M et al..  2017.  Constitutive resistance to viral infection in human CD141 dendritic cells.. Sci Immunol. 2(13)
Peinado H, Zhang H, Matei IR, Costa-Silva B, Hoshino A, Rodrigues G, Psaila B, Kaplan RNatasha, Bromberg JF, Kang Y et al..  2017.  Pre-metastatic niches: organ-specific homes for metastases.. Nat Rev Cancer. 17(5):302-317.
Shi Z, Fujii K, Kovary KM, Genuth NR, Röst HL, Teruel MN, Barna M.  2017.  Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide.. Mol Cell. 67(1):71-83.e7.
Cepika A-M, Banchereau R, Segura E, Ohouo M, Cantarel B, Goller K, Cantrell V, Ruchaud E, Gatewood E, Nguyen P et al..  2017.  A multidimensional blood stimulation assay reveals immune alterations underlying systemic juvenile idiopathic arthritis.. J Exp Med. 214(11):3449-3466.
Huang Y, Rajappa P, Hu W, Hoffman C, Cisse B, Kim J-H, Gorge E, Yanowitch R, Cope W, Vartanian E et al..  2017.  A proangiogenic signaling axis in myeloid cells promotes malignant progression of glioma.. J Clin Invest. 127(5):1826-1838.
Kim D, Zeng MY, Nunez G.  2017.  The interplay between host immune cells and gut microbiota in chronic inflammatory diseases.. Exp Mol Med. 49(5):e339.
Sansone P, Berishaj M, Rajasekhar VK, Ceccarelli C, Chang Q, Strillacci A, Savini C, Shapiro L, Bowman RL, Mastroleo C et al..  2017.  Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles.. Cancer Res. 77(8):1927-1941.
Sharma A, Xu Y, Sung B, C Vincent T, Worgall TS, Worgall S.  2017.  Regulation of the Coxsackie and adenovirus receptor expression is dependent on cystic fibrosis transmembrane regulator in airway epithelial cells.. Cell Microbiol. 19(2)
Perzanowski MS, Ono JG, Acosta LM, Kim BI, Divjan A, Miller R, Rundle A, Worgall S, Worgall TS.  2017.  Distinct Serum Sphingolipid Profiles among School-aged Children with Exercise-induced Wheeze and Asthma Persistence.. Am J Respir Crit Care Med. 195(8):1068-1070.
Stone A, Friedman DNovetsky, Worgall S, Kushner BH, Wolden SL, Modak S, LaQuaglia MP, Wu X, Cheung N-K, Sklar CA.  2017.  Long-term Pulmonary Outcomes in Pediatric Survivors of High-risk Neuroblastoma.. J Pediatr Hematol Oncol. 39(7):547-554.
Gomi R, Sharma A, Wu W, Sung B, Worgall S.  2017.  Post-exposure immunization by capsid-modified AdC7 vector expressing Pseudomonas aeruginosa OprF clears P. aeruginosa respiratory infection.. Vaccine. 35(51):7174-7180.
Zhang H, Lyden DC.  2017.  Bone voyage-Osteoblasts remotely control tumors.. Science. 358(6367):1127-1128.
Pickard JM, Zeng MY, Caruso R, Nunez G.  2017.  Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease.. Immunol Rev. 279(1):70-89.
Sansone P, Savini C, Kurelac I, Chang Q, Amato LBenedetta, Strillacci A, Stepanova A, Iommarini L, Mastroleo C, Daly LA et al..  2017.  Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.. Proc Natl Acad Sci U S A. 114(43):E9066-E9075.

2016

André Mdo Rosári, Pedro A, Lyden DC.  2016.  Cancer Exosomes as Mediators of Drug Resistance.. Methods Mol Biol. 1395:229-39.
Blankley S, Graham CM, Turner J, Berry MPR, Bloom CI, Xu Z, Pascual V, Banchereau J, Chaussabel D, Breen R et al..  2016.  The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis.. PLoS One. 11(10):e0162220.
Kim TWhan, Hong S, Lin Y, Murat E, Joo HM, Kim T, Pascual V, Liu Y-J.  2016.  Transcriptional Repression of IFN Regulatory Factor 7 by MYC Is Critical for Type I IFN Production in Human Plasmacytoid Dendritic Cells.. J Immunol. 197(8):3348-3359.
Kaya N, Alsagob M, D'Adamo MCristina, Al-Bakheet A, Hasan S, Muccioli M, Almutairi FB, Almass R, Aldosary M, Monies D et al..  2016.  deficiency leads to a syndrome of abnormal striatum, congenital cataract and intellectual disability.. J Med Genet. 53(11):786-792.
Zeng MY, Cisalpino D, Varadarajan S, Hellman J, H Warren S, Cascalho M, Inohara N, Nunez G.  2016.  Gut Microbiota-Induced Immunoglobulin G Controls Systemic Infection by Symbiotic Bacteria and Pathogens.. Immunity. 44(3):647-658.
Colak D, Alaiya AA, Kaya N, Muiya NP, AlHarazi O, Shinwari Z, Andres E, Dzimiri N.  2016.  Integrated Left Ventricular Global Transcriptome and Proteome Profiling in Human End-Stage Dilated Cardiomyopathy.. PLoS One. 11(10):e0162669.
He Y, Zeng MY, Yang D, Motro B, Nunez G.  2016.  NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux.. Nature. 530(7590):354-7.
Al-Harazi O, Insaif SAl, Al-Ajlan MA, Kaya N, Dzimiri N, Colak D.  2016.  Integrated Genomic and Network-Based Analyses of Complex Diseases and Human Disease Network.. J Genet Genomics. 43(6):349-67.
Shaheen R, Anazi S, Ben-Omran T, Seidahmed MZain, L Caddle B, Palmer K, Ali R, Alshidi T, Hagos S, Goodwin L et al..  2016.  Mutations in SMG9, Encoding an Essential Component of Nonsense-Mediated Decay Machinery, Cause a Multiple Congenital Anomaly Syndrome in Humans and Mice.. Am J Hum Genet. 98(4):643-52.
Doğan HKılınçk, Mutlu E, Köksoy S, Yılmaz VT, Koçak H, Colak D, Mutlu D, Günseren F, Dinçkan A, Aliosmanoğlu İ et al..  2016.  [Monitoring of cytomegalovirus-specific CD4+ and CD8+ T cell responses by cytokine flow cytometry in renal transplant recipients].. Mikrobiyol Bul. 50(2):224-35.
Sharma A, Wu W, Sung B, Huang J, Tsao T, Li X, Gomi R, Tsuji M, Worgall S.  2016.  Respiratory Syncytial Virus (RSV) Pulmonary Infection in Humanized Mice Induces Human Anti-RSV Immune Responses and Pathology.. J Virol. 90(10):5068-5074.
Ghazi NG, Abboud EB, Nowilaty SR, Alkuraya H, Alhommadi A, Cai H, Hou R, Deng W-T, Boye SL, Almaghamsi A et al..  2016.  Treatment of retinitis pigmentosa due to MERTK mutations by ocular subretinal injection of adeno-associated virus gene vector: results of a phase I trial.. Hum Genet. 135(3):327-43.
Traube C, Mauer EA, Gerber LM, Kaur S, Joyce C, Kerson A, Carlo C, Notterman D, Worgall S, Silver G et al..  2016.  Cost Associated With Pediatric Delirium in the ICU.. Crit Care Med. 44(12):e1175-e1179.
Grom AA, Ilowite NT, Pascual V, Brunner HI, Martini A, Lovell D, Ruperto N, Leon K, Lheritier K, Abrams K.  2016.  Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab.. Arthritis Rheumatol. 68(1):218-28.
Al-Hassnan ZN, Shinwari ZMa, Wakil SM, Tulbah S, Mohammed S, Rahbeeni Z, Alghamdi M, Rababh M, Colak D, Kaya N et al..  2016.  A substitution mutation in cardiac ubiquitin ligase, FBXO32, is associated with an autosomal recessive form of dilated cardiomyopathy.. BMC Med Genet. 17:3.
Nguyen M, Sharma A, Wu W, Gomi R, Sung B, Hospodsky D, Angenent LT, Worgall S.  2016.  The fermentation product 2,3-butanediol alters P. aeruginosa clearance, cytokine response and the lung microbiome.. ISME J. 10(12):2978-2983.
Cols M, Rahman A, Maglione PJ, Garcia-Carmona Y, Simchoni N, Ko H-BM, Radigan L, Cerutti A, Blankenship D, Pascual V et al..  2016.  Expansion of inflammatory innate lymphoid cells in patients with common variable immune deficiency.. J Allergy Clin Immunol. 137(4):1206-1215.e6.
Becker A, Thakur BKumar, Weiss JMitchell, Kim HSang, Peinado H, Lyden DC.  2016.  Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis.. Cancer Cell. 30(6):836-848.
Dağlar DEren, Öngüt G, Colak D, Özkul A, Mutlu D, Zeytinoğlu A, Midilli K, Gökahmetoğlu S, Günseren F, Öğünç D et al..  2016.  [Determination of cytomegalovirus glycoprotein B genotypes in different geographical regions and different patient groups in Turkey].. Mikrobiyol Bul. 50(1):53-62.
Veerappan A, Thompson M, Savage AR, Silverman ML, Chan WS, Sung B, Summers B, Montelione KC, Benedict P, Groh B et al..  2016.  Mast cells and exosomes in hyperoxia-induced neonatal lung disease.. Am J Physiol Lung Cell Mol Physiol. 310(11):L1218-32.
Kim TWhan, Hong S, Talukder AH, Pascual V, Liu Y-J.  2016.  Grancalcin (GCA) modulates Toll-like receptor 9 (TLR9) mediated signaling through its direct interaction with TLR9.. Eur J Immunol. 46(3):712-24.
Peinado H, Alecˇković M, Lavotshkin S, Matei IR, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar CM et al..  2016.  Corrigendum: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.. Nat Med. 22(12):1502.
Heinonen S, Jartti T, Garcia C, Oliva S, Smitherman C, Anguiano E, Piters WAA de Ste, Vuorinen T, Ruuskanen O, Dimo B et al..  2016.  Rhinovirus Detection in Symptomatic and Asymptomatic Children: Value of Host Transcriptome Analysis.. Am J Respir Crit Care Med. 193(7):772-82.
Rampersaud S, Fang J, Wei Z, Fabijanic K, Silver S, Jaikaran T, Ruiz Y, Houssou M, Yin Z, Zheng S et al..  2016.  The Effect of Cage Shape on Nanoparticle-Based Drug Carriers: Anticancer Drug Release and Efficacy via Receptor Blockade Using Dextran-Coated Iron Oxide Nanocages.. Nano Lett. 16(12):7357-7363.
Kenific CM, Nogués L, Lyden DC.  2016.  Pre-Metastatic Niche Formation Has Taken Its TOLL.. Cancer Cell. 30(2):189-191.
Blankley S, Graham CM, Levin J, Turner J, Berry MPR, Bloom CI, Xu Z, Pascual V, Banchereau J, Chaussabel D et al..  2016.  A 380-gene meta-signature of active tuberculosis compared with healthy controls.. Eur Respir J. 47(6):1873-6.
Thompson EM, Hielscher T, Bouffet E, Remke M, Luu B, Gururangan S, McLendon RE, Bigner DD, Lipp ES, Perreault S et al..  2016.  Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis.. Lancet Oncol. 17(4):484-495.
Pitt JM, Blankley S, Potempa K, Graham CM, Moreira-Teixeira L, McNab FW, Howes A, Stavropoulos E, Pascual V, Banchereau J et al..  2016.  Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling.. PLoS One. 11(2):e0150251.
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2015

Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BKumar, Becker A, Hoshino A, Mark MTešić, Molina H et al..  2015.  Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver.. Nat Cell Biol. 17(6):816-26.
Anandasabapathy N, Breton G, Hurley A, Caskey M, Trumpfheller C, Sarma P, Pring J, Pack M, Buckley N, Matei I et al..  2015.  Efficacy and safety of CDX-301, recombinant human Flt3L, at expanding dendritic cells and hematopoietic stem cells in healthy human volunteers.. Bone Marrow Transplant. 50(7):924-30.
Hoshino A, Costa-Silva B, Shen T-L, Rodrigues G, Hashimoto A, Mark MTesic, Molina H, Kohsaka S, Di Giannatale A, Ceder S et al..  2015.  Tumour exosome integrins determine organotropic metastasis.. Nature. 527(7578):329-35.
Ono JG, Worgall TS, Worgall S.  2015.  Airway reactivity and sphingolipids-implications for childhood asthma.. Mol Cell Pediatr. 2(1):13.
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Bagaitkar J, Pech NK, Ivanov S, Austin A, Zeng MYue, Pallat S, Huang G, Randolph GJ, Dinauer MC.  2015.  NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1α/G-CSF axis.. Blood. 126(25):2724-33.
Kamada N, Sakamoto K, Seo S-U, Zeng MY, Kim Y-G, Cascalho M, Vallance BA, Puente JL, Nunez G.  2015.  Humoral Immunity in the Gut Selectively Targets Phenotypically Virulent Attaching-and-Effacing Bacteria for Intraluminal Elimination.. Cell Host Microbe. 17(5):617-27.
Ahrends R, Niewiadomski P, Teruel MN, Rohatgi R.  2015.  Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry.. Methods Mol Biol. 1322:105-23.
Ota A, Kovary KM, Wu OH, Ahrends R, Shen W-J, Costa MJ, Feldman BJ, Kraemer FB, Teruel MN.  2015.  Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice.. J Lipid Res. 56(5):1068-78.
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Theivanthiran B, Kathania M, Zeng M, Anguiano E, Basrur V, Vandergriff T, Pascual V, Wei W-Z, Massoumi R, Venuprasad K.  2015.  The E3 ubiquitin ligase Itch inhibits p38α signaling and skin inflammation through the ubiquitylation of Tab1.. Sci Signal. 8(365):ra22.
Jacquemin C, Schmitt N, Contin-Bordes C, Liu Y, Narayanan P, Seneschal J, Maurouard T, Dougall D, Davizon ESpence, Dumortier H et al..  2015.  OX40 Ligand Contributes to Human Lupus Pathogenesis by Promoting T Follicular Helper Response.. Immunity. 42(6):1159-70.
Conejero L, Potempa K, Graham CM, Spink N, Blankley S, Salguero FJ, Pankla-Sranujit R, Khaenam P, Banchereau JF, Pascual V et al..  2015.  The Blood Transcriptome of Experimental Melioidosis Reflects Disease Severity and Shows Considerable Similarity with the Human Disease.. J Immunol. 195(7):3248-3261.
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Wang X, Dubuc AM, Ramaswamy V, Mack S, Gendoo DMA, Remke M, Wu X, Garzia L, Luu B, Cavalli F et al..  2015.  Medulloblastoma subgroups remain stable across primary and metastatic compartments.. Acta Neuropathol. 129(3):449-57.
Papaspyridonos M, Matei I, Huang Y, André Mdo Rosári, Brazier-Mitouart H, Waite JC, Chan AS, Kalter J, Ramos I, Wu Q et al..  2015.  Id1 suppresses anti-tumour immune responses and promotes tumour progression by impairing myeloid cell maturation.. Nat Commun. 6:6840.
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