Title | Metastasis. |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Lyden D, Ghajar CM, Correia ALuĂsa, Aguirre-Ghiso JA, Cai S, Rescigno M, Zhang P, Hu G, Fendt S-M, Boire A, Weichselbaum RR, Katipally RR |
Journal | Cancer Cell |
Volume | 40 |
Issue | 8 |
Pagination | 787-791 |
Date Published | 2022 Aug 08 |
ISSN | 1878-3686 |
Keywords | Humans, Immune System, Neoplasm Metastasis, Neoplasms, Tumor Microenvironment |
Abstract | Metastasis, the major cause of cancer death, represents one of the major challenges in oncology. Scientists are still trying to understand the biological basis underlying the dissemination and outgrowth of tumor cells, why these cells can remain dormant for years, how they become resistant to the immune system or cytotoxic effects of systemic therapy, and how they interact with their new microenvironment. We asked experts to discuss some of the unknowns, advances, and areas of opportunity related to cancer metastasis. |
DOI | 10.1016/j.ccell.2022.07.010 |
Custom 1 | |
Alternate Journal | Cancer Cell |
PubMed ID | 35944497 |