Title | Good intentions gone wrong: The B cell block to epithelial repair. |
Publication Type | Journal Article |
Year of Publication | 2022 |
Authors | Grasset EK, Alenghat T |
Journal | Immunity |
Volume | 55 |
Issue | 12 |
Pagination | 2222-2224 |
Date Published | 2022 Dec 13 |
ISSN | 1097-4180 |
Keywords | Colon, Epithelial Cells, Intention, Intestinal Mucosa |
Abstract | Cellular dynamics that influence mucosal healing are not well understood. In this issue of Immunity, Frede, Czarnewski, Monasterio et al. find that B cells accumulate in the colon following intestinal injury. These B cells impair epithelial repair by hindering local stromal-epithelial interactions. |
DOI | 10.1016/j.immuni.2022.11.011 |
Custom 1 | |
Alternate Journal | Immunity |
PubMed ID | 36516815 |
PubMed Central ID | PMC11008460 |
Grant List | R01 DK114123 / DK / NIDDK NIH HHS / United States R01 DK116868 / DK / NIDDK NIH HHS / United States |