Good intentions gone wrong: The B cell block to epithelial repair.

TitleGood intentions gone wrong: The B cell block to epithelial repair.
Publication TypeJournal Article
Year of Publication2022
AuthorsGrasset EK, Alenghat T
JournalImmunity
Volume55
Issue12
Pagination2222-2224
Date Published2022 Dec 13
ISSN1097-4180
KeywordsColon, Epithelial Cells, Intention, Intestinal Mucosa
Abstract

Cellular dynamics that influence mucosal healing are not well understood. In this issue of Immunity, Frede, Czarnewski, Monasterio et al. find that B cells accumulate in the colon following intestinal injury. These B cells impair epithelial repair by hindering local stromal-epithelial interactions.

DOI10.1016/j.immuni.2022.11.011
Custom 1

https://www.ncbi.nlm.nih.gov/pubmed/36516815?dopt=Abstract

Alternate JournalImmunity
PubMed ID36516815
PubMed Central IDPMC11008460
Grant ListR01 DK114123 / DK / NIDDK NIH HHS / United States
R01 DK116868 / DK / NIDDK NIH HHS / United States

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