| Title | Tumor Extracellular Vesicles Impede Interferon Alert Responses. |
| Publication Type | Journal Article |
| Year of Publication | 2019 |
| Authors | Kenific CM, Wang G, Lyden DC |
| Journal | Cancer Cell |
| Volume | 35 |
| Issue | 1 |
| Pagination | 3-5 |
| Date Published | 2019 01 14 |
| ISSN | 1878-3686 |
| Keywords | Extracellular Vesicles, Humans, Interferons, Neoplasms, Oxysterols |
| Abstract | Tumor-derived extracellular vesicles promote metastasis by inducing functional changes in cells at pre-metastatic sites conducive for tumor cell colonization. In this issue of Cancer Cell, Ortiz and colleagues show that type I interferon regulates extracellular vesicle uptake and that modulating this pathway holds promise for treating metastasis. |
| DOI | 10.1016/j.ccell.2018.12.006 |
| Custom 1 | |
| Alternate Journal | Cancer Cell |
| PubMed ID | 30645974 |