Sex-biased gut dopamine signaling in multiple sclerosis.

TitleSex-biased gut dopamine signaling in multiple sclerosis.
Publication TypeJournal Article
Year of Publication2023
AuthorsYu S, Zeng MY
JournalImmunity
Volume56
Issue12
Pagination2674-2676
Date Published2023 Dec 12
ISSN1097-4180
KeywordsAnimals, Dopamine, Female, Inflammation, Mice, Multiple Sclerosis, Sexism
Abstract

Multiple sclerosis shows a strong sex bias, with unclear mechanisms. In this issue of Immunity, Peng et al. elucidate a female-biased increase in intestinal dopamine signaling that diminishes protective Lactobacillus and exacerbates inflammation in a mouse model of multiple sclerosis.

DOI10.1016/j.immuni.2023.11.016
Custom 1

https://www.ncbi.nlm.nih.gov/pubmed/38091947?dopt=Abstract

Alternate JournalImmunity
PubMed ID38091947
PubMed Central IDPMC10908588
Grant ListK01 DK114376 / DK / NIDDK NIH HHS / United States
R01 HD110118 / HD / NICHD NIH HHS / United States
R01 HL169989 / HL / NHLBI NIH HHS / United States
R21 CA270998 / CA / NCI NIH HHS / United States

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