Gale and Ira Drukier Institute for Children's Health
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2022
Shaashua L, Ben-Shmuel A, Pevsner-Fischer M, Friedman G, Levi-Galibov O, Nandakumar S, Barki D, Nevo R, Brown LE, Zhang W et al..  2022.  BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling.. Nat Commun. 13(1):6513.
Yu F, Courjaret R, Elmi A, Adap EAlcantara, Orie NN, Zghyer F, Hubrack S, Hayat S, Asaad N, Worgall S et al..  2022.  Chronic reduction of store operated Ca2+ entry is viable therapeutically but is associated with cardiovascular complications.. J Physiol. 600(22):4827-4848.
Zhang Z-B, Sinha J, Bahrami-Nejad Z, Teruel MN.  2022.  The circadian clock mediates daily bursts of cell differentiation by periodically restricting cell-differentiation commitment.. Proc Natl Acad Sci U S A. 119(33):e2204470119.
Ortiz R, Kluwe B, Lazarus S, Teruel MN, Joseph JJ.  2022.  Cortisol and cardiometabolic disease: a target for advancing health equity.. Trends Endocrinol Metab. 33(11):786-797.
Choi J, Cho HYeon, Jeon J, Kim K-A, Han YDae, Ahn JBae, Wortzel I, Lyden D, Kim HSang.  2022.  Detection of circulating KRAS mutant DNA in extracellular vesicles using droplet digital PCR in patients with colon cancer.. Front Oncol. 12:1067210.
Heras A, Gomi R, Young M, Chang CL, Wasserman E, Sharma A, Wu W, Gu J, Balaji U, White R et al..  2022.  Dietary long-chain omega 3 fatty acids modify sphingolipid metabolism to facilitate airway hyperreactivity.. Sci Rep. 12(1):19735.
Bahrami-Nejad Z, Zhang Z-B, Tholen S, Sharma S, Rabiee A, Zhao ML, Kraemer FB, Teruel MN.  2022.  Early enforcement of cell identity by a functional component of the terminally differentiated state.. PLoS Biol. 20(12):e3001900.
Strillacci A, Sansone P, Rajasekhar VK, Turkekul M, Boyko V, Meng F, Houck-Loomis B, Brown D, Berger MF, Hendrickson RC et al..  2022.  ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance.. NPJ Breast Cancer. 8(1):96.
Lucaci AG, Notaras MJ, Pond SLKosakovs, Colak D.  2022.  The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease? Transl Psychiatry. 12(1):258.
Lucotti S, Kenific CM, Zhang H, Lyden D.  2022.  Extracellular vesicles and particles impact the systemic landscape of cancer.. EMBO J. 41(18):e109288.
Tholen S, Patel R, Agas A, Kovary KM, Rabiee A, Nicholls HT, Bielczyk-Maczyńska E, Yang W, Kraemer FB, Teruel MN.  2022.  Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy.. Cell Rep. 39(13):111018.
Grasset EK, Alenghat T.  2022.  Good intentions gone wrong: The B cell block to epithelial repair.. Immunity. 55(12):2222-2224.
Brown JA, Sanidad KZ, Lucotti S, Lieber CM, Cox RM, Ananthanarayanan A, Basu S, Chen J, Shan M, Amir M et al..  2022.  Gut microbiota-derived metabolites confer protection against SARS-CoV-2 infection.. Gut Microbes. 14(1):2105609.
Wasserman E, Gomi R, Sharma A, Hong S, Bareja R, Gu J, Balaji U, Veerappan A, Kim BI, Wu W et al..  2022.  Human Rhinovirus Infection of the Respiratory Tract Affects Sphingolipid Synthesis.. Am J Respir Cell Mol Biol. 66(3):302-311.
Bolton MJ, Arevalo CP, Griesman T, Li SHang, Bates P, Wilson PC, Hensley SE.  2022.  IgG3 subclass antibodies recognize antigenically drifted influenza viruses and SARS-CoV-2 variants through efficient bivalent binding.. bioRxiv.
Arifuzzaman M, Won THyung, Li T-T, Yano H, Digumarthi S, Heras AF, Zhang W, Parkhurst CN, Kashyap S, Jin W-B et al..  2022.  Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.. Nature. 611(7936):578-584.
Sant AJ, Wilson PC.  2022.  Learning from our differences.. Nat Immunol. 23(10):1403-1404.
Li L, Changrob S, Fu Y, Stovicek O, Guthmiller JJ, McGrath JJC, Dugan HL, Stamper CT, Zheng N-Y, Huang M et al..  2022.  Librator: a platform for the optimized analysis, design, and expression of mutable influenza viral antigens.. Brief Bioinform. 23(2)
Sanidad KZ, Amir M, Ananthanarayanan A, Singaraju A, Shiland NB, Hong HS, Kamada N, Inohara N, Nunez G, Zeng MY.  2022.  Maternal gut microbiome-induced IgG regulates neonatal gut microbiome and immunity.. Sci Immunol. 7(72):eabh3816.
McGrath JJC, Li L, Wilson PC.  2022.  Memory B cell diversity: insights for optimized vaccine design.. Trends Immunol. 43(5):343-354.
Lyden D, Ghajar CM, Correia ALuísa, Aguirre-Ghiso JA, Cai S, Rescigno M, Zhang P, Hu G, Fendt S-M, Boire A et al..  2022.  Metastasis.. Cancer Cell. 40(8):787-791.
Khan I, Gril B, Hoshino A, Yang HH, Lee MP, Difilippantonio S, Lyden DC, Steeg PS.  2022.  Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems.. Clin Exp Metastasis.
Huang Z, You X, Chen L, Du Y, Brodeur K, Jee H, Wang Q, Linder G, Darbousset R, Cunin P et al..  2022.  mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome.. Nat Commun. 13(1):6915.
Leonardi I, Gao IH, Lin W-Y, Allen M, Li XV, Fiers WD, De Celie MBialt, Putzel GG, Yantiss RK, Johncilla M et al..  2022.  Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity.. Cell. 185(5):831-846.e14.
Stankovic IN, Colak D.  2022.  Prenatal Drugs and Their Effects on the Developing Brain: Insights From Three-Dimensional Human Organoids.. Front Neurosci. 16:848648.