Gale and Ira Drukier Institute for Children's Health
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2021
Grunberg N, Pevsner-Fischer M, Goshen-Lago T, Diment J, Stein Y, Lavon H, Mayer S, Levi-Galibov O, Friedman G, Ofir-Birin Y et al..  2021.  Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.. Cancer Res. 81(7):1639-1653.
Altman MC, Rinchai D, Baldwin N, Toufiq M, Whalen E, Garand M, Kabeer BSyed Ahame, Alfaki M, Presnell SR, Khaenam P et al..  2021.  Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.. Nat Commun. 12(1):4385.
Cullen SM, Hassan N, Smith-Raska M.  2021.  Effects of non-inherited ancestral genotypes on offspring phenotypes.. Biol Reprod.
Caielli S, Cardenas J, de Jesus AAlmeida, Baisch J, Walters L, Blanck JPhilippe, Balasubramanian P, Stagnar C, Ohouo M, Hong S et al..  2021.  Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE.. Cell.
Kenific CM, Zhang H, Lyden D.  2021.  An exosome pathway without an ESCRT.. Cell Res. 31(2):105-106.
Bojmar L, Kim HSang, Tobias GC, Vatter FAPelissie, Lucotti S, Gyan KEnnu, Kenific CM, Wan Z, Kim K-A, Kim DA et al..  2021.  Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids.. STAR Protoc. 2(1):100225.
Vatter FAPelissie, Cioffi M, Hanna SJ, Castarede I, Caielli S, Pascual V, Matei I, Lyden D.  2021.  Extracellular vesicle- and particle-mediated communication shapes innate and adaptive immune responses.. J Exp Med. 218(8)
Jones GD, Brandt WS, Shen R, Sanchez-Vega F, Tan KSee, Martin A, Zhou J, Berger M, Solit DB, Schultz N et al..  2021.  A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.. JAMA Surg. 156(2):e205601.
Teng F, Tachó-Piñot R, Sung B, Farber DL, Worgall S, Hammad H, Lambrecht BN, Hepworth MR, Sonnenberg GF.  2021.  ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.. Cell Rep. 37(8):110051.
Amir M, Zeng MY.  2021.  Immune imprinting in utero.. Science. 373(6558):967-968.
Li L, Dugan HL, Stamper CT, Lan LYu-Ling, Asby NW, Knight M, Stovicek O, Zheng N-Y, Madariaga MLucia, Shanmugarajah K et al..  2021.  Improved integration of single-cell transcriptome and surface protein expression by LinQ-View.. Cell Rep Methods. 1(4):100056.
Winkler A, Sun W, De S, Jiao A, M Sharif N, Symanowicz PT, Athale S, Shin JH, Wang J, Jacobson BA et al..  2021.  The IRAK4 kinase inhibitor PF-06650833 blocks inflammation in preclinical models of rheumatologic disease and in humans enrolled in a randomized clinical trial.. Arthritis Rheumatol.
Jones GD, Caso R, Tan KSee, Mastrogiacomo B, Sanchez-Vega F, Liu Y, Connolly JG, Murciano-Goroff YR, Bott MJ, Adusumilli PS et al..  2021.  KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma.. Clin Cancer Res. 27(9):2604-2612.
García-Silva S, Benito-Martin A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AAmor et al..  2021.  Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism.. Nat Cancer. 2(12):1387-1405.
Ono JG, Worgall S.  2021.  More Evidence for Inborn Dysregulation of Sphingolipid Metabolism in Children with Asthma? Am J Respir Crit Care Med. 203(7):792-793.
Doron I, Mesko M, Li XV, Kusakabe T, Leonardi I, Shaw DG, Fiers WD, Lin W-Y, Bialt-DeCelie M, Román E et al..  2021.  Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn's disease.. Nat Microbiol. 6(12):1493-1504.
Notaras M, Lodhi A, Barrio-Alonso E, Foord C, Rodrick T, Jones D, Fang H, Greening D, Colak D.  2021.  Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids.. Mol Psychiatry.
Wasserman E, Worgall S.  2021.  Perinatal origins of chronic lung disease: mechanisms-prevention-therapy-sphingolipid metabolism and the genetic and perinatal origins of childhood asthma.. Mol Cell Pediatr. 8(1):22.
Shor RE, Dai J, Lee S-Y, Pisarsky L, Matei I, Lucotti S, Lyden D, Bissell MJ, Ghajar CM.  2021.  The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings.. Mol Oncol.
Notaras M, Lodhi A, Fang H, Greening D, Colak D.  2021.  The proteomic architecture of schizophrenia iPSC-derived cerebral organoids reveals alterations in GWAS and neuronal development factors.. Transl Psychiatry. 11(1):541.
Lawlor N, Nehar-Belaid D, Grassmann JDS, Stoeckius M, Smibert P, Stitzel ML, Pascual V, Banchereau J, Williams A, Ucar D.  2021.  Single Cell Analysis of Blood Mononuclear Cells Stimulated Through Either LPS or Anti-CD3 and Anti-CD28.. Front Immunol. 12:636720.
Wang G, Zhang H, Lyden D.  2021.  Tumour-regulated anorexia preceding cachexia.. Nat Cell Biol. 23(2):111-113.
2020
Bezdan D, Grigorev K, Meydan C, Vatter FAPelissie, Cioffi M, Rao V, MacKay M, Nakahira K, Burnham P, Afshinnekoo E et al..  2020.  Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.. iScience. 23(12):101844.
Ono JG, Kim BI, Zhao Y, Christos PJ, Tesfaigzi Y, Worgall TS, Worgall S.  2020.  Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes.. J Clin Invest. 130(2):921-926.
Senaldi L, Smith-Raska M.  2020.  Evidence for germline non-genetic inheritance of human phenotypes and diseases.. Clin Epigenetics. 12(1):136.