Gale and Ira Drukier Institute for Children's Health
Found 253 results
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2022
Brown GJ, Canete PF, Wang H, Medhavy A, Bones J, Roco JA, He Y, Qin Y, Cappello J, Ellyard JI et al..  2022.  TLR7 gain-of-function genetic variation causes human lupus.. Nature.
Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Ganesh KShobana, Cho S, Endress J, Schild T et al..  2022.  Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression.. Nat Commun. 13(1):6239.
2021
Tycko J, Adam VS, Crosariol M, Ohlstein J, Sanmiguel J, Tretiakova AP, Roy S, Worgall S, Wilson JM, Limberis MP.  2021.  Adeno-Associated Virus Vector-Mediated Expression of Antirespiratory Syncytial Virus Antibody Prevents Infection in Mouse Airways.. Hum Gene Ther.
Wan Z, Pascual V.  2021.  Breaching self-tolerance by targeting the gatekeeper.. J Exp Med. 218(5)
Guthmiller JJ, Han J, Utset HA, Li L, Lan LYu-Ling, Henry C, Stamper CT, McMahon M, O'Dell G, Fernández-Quintero ML et al..  2021.  Broadly neutralizing antibodies target a hemagglutinin anchor epitope.. Nature.
Norgard RJ, Pitarresi JR, Maddipati R, Aiello-Couzo NM, Balli D, Li J, Yamazoe T, Wengyn MD, Millstein ID, Folkert IW et al..  2021.  Calcium signaling induces a partial EMT.. EMBO Rep. :e51872.
Grunberg N, Pevsner-Fischer M, Goshen-Lago T, Diment J, Stein Y, Lavon H, Mayer S, Levi-Galibov O, Friedman G, Ofir-Birin Y et al..  2021.  Cancer-Associated Fibroblasts Promote Aggressive Gastric Cancer Phenotypes via Heat Shock Factor 1-Mediated Secretion of Extracellular Vesicles.. Cancer Res. 81(7):1639-1653.
Altman MC, Rinchai D, Baldwin N, Toufiq M, Whalen E, Garand M, Kabeer BSyed Ahame, Alfaki M, Presnell SR, Khaenam P et al..  2021.  Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.. Nat Commun. 12(1):4385.
Cullen SM, Hassan N, Smith-Raska M.  2021.  Effects of non-inherited ancestral genotypes on offspring phenotypes.. Biol Reprod.
Caielli S, Cardenas J, de Jesus AAlmeida, Baisch J, Walters L, Blanck JPhilippe, Balasubramanian P, Stagnar C, Ohouo M, Hong S et al..  2021.  Erythroid mitochondrial retention triggers myeloid-dependent type I interferon in human SLE.. Cell.
Kenific CM, Zhang H, Lyden D.  2021.  An exosome pathway without an ESCRT.. Cell Res. 31(2):105-106.
Bojmar L, Kim HSang, Tobias GC, Vatter FAPelissie, Lucotti S, Gyan KEnnu, Kenific CM, Wan Z, Kim K-A, Kim DA et al..  2021.  Extracellular vesicle and particle isolation from human and murine cell lines, tissues, and bodily fluids.. STAR Protoc. 2(1):100225.
Vatter FAPelissie, Cioffi M, Hanna SJ, Castarede I, Caielli S, Pascual V, Matei I, Lyden D.  2021.  Extracellular vesicle- and particle-mediated communication shapes innate and adaptive immune responses.. J Exp Med. 218(8)
Jones GD, Brandt WS, Shen R, Sanchez-Vega F, Tan KSee, Martin A, Zhou J, Berger M, Solit DB, Schultz N et al..  2021.  A Genomic-Pathologic Annotated Risk Model to Predict Recurrence in Early-Stage Lung Adenocarcinoma.. JAMA Surg. 156(2):e205601.
Teng F, Tachó-Piñot R, Sung B, Farber DL, Worgall S, Hammad H, Lambrecht BN, Hepworth MR, Sonnenberg GF.  2021.  ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.. Cell Rep. 37(8):110051.
Amir M, Zeng MY.  2021.  Immune imprinting in utero.. Science. 373(6558):967-968.
Li L, Dugan HL, Stamper CT, Lan LYu-Ling, Asby NW, Knight M, Stovicek O, Zheng N-Y, Madariaga MLucia, Shanmugarajah K et al..  2021.  Improved integration of single-cell transcriptome and surface protein expression by LinQ-View.. Cell Rep Methods. 1(4):100056.
Winkler A, Sun W, De S, Jiao A, M Sharif N, Symanowicz PT, Athale S, Shin JH, Wang J, Jacobson BA et al..  2021.  The IRAK4 kinase inhibitor PF-06650833 blocks inflammation in preclinical models of rheumatologic disease and in humans enrolled in a randomized clinical trial.. Arthritis Rheumatol.
Jones GD, Caso R, Tan KSee, Mastrogiacomo B, Sanchez-Vega F, Liu Y, Connolly JG, Murciano-Goroff YR, Bott MJ, Adusumilli PS et al..  2021.  KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma.. Clin Cancer Res. 27(9):2604-2612.
García-Silva S, Benito-Martin A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AAmor et al..  2021.  Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism.. Nat Cancer. 2(12):1387-1405.
Ono JG, Worgall S.  2021.  More Evidence for Inborn Dysregulation of Sphingolipid Metabolism in Children with Asthma? Am J Respir Crit Care Med. 203(7):792-793.
Doron I, Mesko M, Li XV, Kusakabe T, Leonardi I, Shaw DG, Fiers WD, Lin W-Y, Bialt-DeCelie M, Román E et al..  2021.  Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn's disease.. Nat Microbiol. 6(12):1493-1504.
Notaras M, Lodhi A, Barrio-Alonso E, Foord C, Rodrick T, Jones D, Fang H, Greening D, Colak D.  2021.  Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids.. Mol Psychiatry.
Wasserman E, Worgall S.  2021.  Perinatal origins of chronic lung disease: mechanisms-prevention-therapy-sphingolipid metabolism and the genetic and perinatal origins of childhood asthma.. Mol Cell Pediatr. 8(1):22.
Shor RE, Dai J, Lee S-Y, Pisarsky L, Matei I, Lucotti S, Lyden D, Bissell MJ, Ghajar CM.  2021.  The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings.. Mol Oncol.