NEW YORK (September 17) — Dr. Sallie Permar, an eminent physician-scientist who focuses on the treatment and prevention of neonatal viral infections, has been appointed chair of the Department of Pediatrics at Weill Cornell Medicine and pediatrician-in-chief at NewYork-Presbyterian/Weill Cornell Medical Center and NewYork-Presbyterian Komansky Children’s Hospital, effective Dec. 1.Recruited as the Nancy C. Paduano Professor of Pediatrics, Dr. Permar will helm the pediatrics enterprise at Weill...
Abnormal immune activity in lupus, a chronic disease that can cause rashes, fatigue, joint pain, and kidney failure, seems to occur mostly in small subsets of immune cells in patients, potentially enabling better targeting for future treatments, according to a study from scientists at Weill Cornell Medicine and The Jackson Laboratory for Genomic Medicine.
Tiny packets called extracellular vesicles and particles (EVPs), released by cancer and immune cells, contain specific proteins that may serve as reliable biomarkers for diagnosing early-stage cancer, according to investigators at Weill Cornell Medicine and Memorial Sloan Kettering.
Patients with systemic lupus erythematosus (SLE) display a complex blood transcriptome whose cellular origin is poorly resolved. Using single-cell RNA sequencing, we profiled ~276,000 peripheral blood mononuclear cells from 33 children with SLE with different degrees of disease activity and 11 matched controls. Increased expression of interferon-stimulated genes (ISGs) distinguished cells from children with SLE from healthy control cells. The high ISG expression signature (ISGhi) derived from a...
Dr. Sallie Permar, a physician-scientist who investigates the prevention and treatment of neonatal viral infections, and Dr. Stephen Patrick, a neonatologist focused on the impact of the opioid epidemic on pregnant women and infants, have been jointly awarded the fifth annual Gale and Ira Drukier Prize in Children’s Health Research, Weill Cornell Medicine announced today.
Scientists have long known that cells can activate a small set of “rapid-response” genes to fight immediate threats like pathogens. But with so many genes stored in such a tiny package (the micron-scale nucleus), researchers have sought how signals can turn on select genes quickly and to high levels. Dr. Josefowicz’s team and collaborators had a hunch that a hidden code in histones, proteins that package DNA, played a key role in rapid gene expression.
That hunch proved correct when they...
NEW YORK (February 28, 2018) — Dr. Vijay Sankaran, a physician-scientist who investigates the molecular underpinnings of pediatric genetic blood disorders, has been awarded the third annual Gale and Ira Drukier Prize in Children’s Health Research, Weill Cornell Medicine announced today.The Drukier Prize honors an early-career pediatrician whose research has made important contributions toward improving the health of children and adolescents. Dr. Sankaran is a pediatric hematologist and...
