Gale and Ira Drukier Institute for Children's Health
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2021
Winkler A, Sun W, De S, Jiao A, M Sharif N, Symanowicz PT, Athale S, Shin JH, Wang J, Jacobson BA et al..  2021.  The IRAK4 kinase inhibitor PF-06650833 blocks inflammation in preclinical models of rheumatologic disease and in humans enrolled in a randomized clinical trial.. Arthritis Rheumatol.
Jones GD, Caso R, Tan KSee, Mastrogiacomo B, Sanchez-Vega F, Liu Y, Connolly JG, Murciano-Goroff YR, Bott MJ, Adusumilli PS et al..  2021.  KRAS G12C Mutation Is Associated with Increased Risk of Recurrence in Surgically Resected Lung Adenocarcinoma.. Clin Cancer Res. 27(9):2604-2612.
García-Silva S, Benito-Martin A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AAmor et al..  2021.  Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism.. Nat Cancer. 2(12):1387-1405.
Ono JG, Worgall S.  2021.  More Evidence for Inborn Dysregulation of Sphingolipid Metabolism in Children with Asthma? Am J Respir Crit Care Med. 203(7):792-793.
Doron I, Mesko M, Li XV, Kusakabe T, Leonardi I, Shaw DG, Fiers WD, Lin W-Y, Bialt-DeCelie M, Román E et al..  2021.  Mycobiota-induced IgA antibodies regulate fungal commensalism in the gut and are dysregulated in Crohn's disease.. Nat Microbiol. 6(12):1493-1504.
Notaras M, Lodhi A, Barrio-Alonso E, Foord C, Rodrick T, Jones D, Fang H, Greening D, Colak D.  2021.  Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids.. Mol Psychiatry.
Wasserman E, Worgall S.  2021.  Perinatal origins of chronic lung disease: mechanisms-prevention-therapy-sphingolipid metabolism and the genetic and perinatal origins of childhood asthma.. Mol Cell Pediatr. 8(1):22.
Shor RE, Dai J, Lee S-Y, Pisarsky L, Matei I, Lucotti S, Lyden D, Bissell MJ, Ghajar CM.  2021.  The PI3K/mTOR inhibitor Gedatolisib eliminates dormant breast cancer cells in organotypic culture, but fails to prevent metastasis in preclinical settings.. Mol Oncol.
Lawlor N, Nehar-Belaid D, Grassmann JDS, Stoeckius M, Smibert P, Stitzel ML, Pascual V, Banchereau J, Williams A, Ucar D.  2021.  Single Cell Analysis of Blood Mononuclear Cells Stimulated Through Either LPS or Anti-CD3 and Anti-CD28.. Front Immunol. 12:636720.
Wang G, Zhang H, Lyden D.  2021.  Tumour-regulated anorexia preceding cachexia.. Nat Cell Biol. 23(2):111-113.
2020
Bezdan D, Grigorev K, Meydan C, Vatter FAPelissie, Cioffi M, Rao V, MacKay M, Nakahira K, Burnham P, Afshinnekoo E et al..  2020.  Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers.. iScience. 23(12):101844.
Ono JG, Kim BI, Zhao Y, Christos PJ, Tesfaigzi Y, Worgall TS, Worgall S.  2020.  Decreased sphingolipid synthesis in children with 17q21 asthma-risk genotypes.. J Clin Invest. 130(2):921-926.
Senaldi L, Smith-Raska M.  2020.  Evidence for germline non-genetic inheritance of human phenotypes and diseases.. Clin Epigenetics. 12(1):136.
Hoshino A, Kim HSang, Bojmar L, Gyan KEnnu, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S et al..  2020.  Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.. Cell. 182(4):1044-1061.e18.
Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F et al..  2020.  A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.. Cell Stem Cell. 27(1):125-136.e7.
Martinez OM, Bridges ND, Goldmuntz E, Pascual V.  2020.  The immune roadmap for understanding multi-system inflammatory syndrome in children: opportunities and challenges.. Nat Med. 26(12):1819-1824.
Heras AF, Veerappan A, Silver RB, Emala CW, Worgall TS, Perez-Zoghbi J, Worgall S.  2020.  Increasing Sphingolipid Synthesis Alleviates Airway Hyperreactivity.. Am J Respir Cell Mol Biol.
Sanidad KZ, Zeng MY.  2020.  LOS in The Dysbiotic Gut.. Cell Host Microbe. 27(1):11-13.
Nehar-Belaid D, Hong S, Marches R, Chen G, Bolisetty M, Baisch J, Walters L, Punaro M, Rossi RJ, Chung C-H et al..  2020.  Mapping systemic lupus erythematosus heterogeneity at the single-cell level.. Nat Immunol.
Subrahmanyam PB, Holmes TH, Lin D, Su LF, Obermoser G, Banchereau J, Pascual V, García-Sastre A, Albrecht RA, Palucka K et al..  2020.  Mass Cytometry Defines Virus-Specific CD4 T Cells in Influenza Vaccination.. Immunohorizons. 4(12):774-788.
Amir M, Brown JA, Rager SL, Sanidad KZ, Ananthanarayanan A, Zeng MY.  2020.  Maternal Microbiome and Infections in Pregnancy.. Microorganisms. 8(12)
Zhao ML, Rabiee A, Kovary KM, Bahrami-Nejad Z, Taylor B, Teruel MN.  2020.  Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle.. Cell Rep. 31(11):107769.
Sanidad KZ, Zeng MY.  2020.  Neonatal gut microbiome and immunity.. Curr Opin Microbiol. 56:30-37.
Sondhi D, Kaminsky SM, Hackett NR, Pagovich OE, Rosenberg JB, De BP, Chen A, Van de Graaf B, Mezey JG, Mammen GW et al..  2020.  Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2.. Sci Transl Med. 12(572)
Zimmer AS, Steinberg SM, Smart DDee, Gilbert MR, Armstrong TS, Burton E, Houston N, Biassou N, Gril B, Brastianos PK et al..  2020.  Temozolomide in secondary prevention of HER2-positive breast cancer brain metastases.. Future Oncol. 16(14):899-909.