Gale and Ira Drukier Institute for Children's Health
Found 274 results
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2025
Cros A, Rigamonti A, de Juan A, Coillard A, Rieux-Laucat M, Tabtim-On D, Papillon E, Goudot C, Cepika A-M, Banchereau R et al..  2025.  Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes.. J Clin Invest. 135(23)
Halfmann PJ, Patel RS, Duffy A, Wang T, Yasuhara A, Carneal K, Singh A, Rai C, Wilson PC, Kawaoka Y et al..  2025.  Characterization and immunogenicity of nanoparticle vaccines based on Clade 2 and Clade 3 sarbecovirus S2 proteins.. NPJ Vaccines.
Changrob S, Yasuhara A, Park S, Bangaru S, Li L, Troxell CA, Halfmann PJ, Erickson SA, Catanzaro NJ, Yuan M et al..  2025.  Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2.. J Exp Med. 222(12)
Wang Z, Lipshutz A, de la Torre CMartínez, Trzeciak AJ, Liu Z-L, Miranda IC, Lazarov T, Codo AC, Romero-Pichardo JE, Nair A et al..  2025.  Early life high fructose impairs microglial phagocytosis and neurodevelopment.. Nature. 644(8077):759-768.
Permar SR, Wilson PC.  2025.  Evolving rare B cell lineages for an effective HIV vaccine.. Science. 389(6759):455-457.
Lucotti S, Ogitani Y, Kenific CM, Geri J, Kim YHun, Gu J, Balaji U, Bojmar L, Shaashua L, Song Y et al..  2025.  Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2.. Cell.
Gutzeit C, Grasset EK, Matthews DB, Maglione PJ, Britton GJ, Miller H, Magri G, Tomalin L, Stapylton M, Canales-Herrerias P et al..  2025.  Gut IgA functionally interacts with systemic IgG to enhance antipneumococcal vaccine responses.. Sci Adv. 11(7):eado9455.
Brown JA, Amir M, Yu S, Wong DSH, Gu J, Balaji U, Parkhurst CN, Hong S, Hart LR, Carrow HC et al..  2025.  Gut microbiota promotes immune tolerance at the maternal-fetal interface.. Cell.
Fu Y, Feng Z, Erickson SA, Halfmann PJ, Li L, Chervin JC, Troxell CA, Sun J, Yasuhara A, Changrob S et al..  2025.  In Vivo Evolution of Monoclonal Antibody CR3022 to Achieve Cross-Neutralization of SARS-CoV-2 and Implications for Vaccine Strategies Against SARS-Related Viruses.. bioRxiv.
Ucar D, Thibodeau A, Mejias A, Nehar-Belaid D, Marches R, Xu Z, Eryilmaz G, Josefowicz S, Paust S, Pascual V et al..  2025.  Infants display reduced NK cell responses in RSV and increased inflammatory responses in SARS-CoV-2 infections.. Res Sq.
Brown JA, Bashir H, Zeng MY.  2025.  Lifelong partners: Gut microbiota-immune cell interactions from infancy to old age.. Mucosal Immunol.
Guthmiller JJ, Lan LYu-Ling, Li L, Fu Y, Nelson SA, Henry C, Stamper CT, Utset HA, Freyn AW, Han J et al..  2025.  Long-lasting B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins.. Immunity. 58(4):980-996.e7.
Iliev ID, J Blander M, Collins N, Guo C-J, Longman RS, Sonnenberg GF, Zeng MY, Artis D.  2025.  Microbiota-mediated mechanisms of mucosal immunity across the lifespan.. Nat Immunol. 26(10):1645-1659.
Zeng MY, Brown JA.  2025.  A mother's touch: microbial guardians of early immune imprinting.. Trends Immunol.
Halfmann PJ, Patel RS, Loeffler K, Yasuhara A, Van De Velde L-A, Yang JE, Chervin J, Troxell C, Huang M, Zheng N et al..  2025.  Multivalent S2 subunit vaccines provide broad protection against Clade 1 sarbecoviruses in female mice.. Nat Commun. 16(1):462.
McGrath JJC, Park J, Troxell CA, Chervin JC, Li L, Kent JR, Changrob S, Fu Y, Huang M, Zheng N-Y et al..  2025.  Mutability and hypermutation antagonize immunoglobulin codon optimality.. Mol Cell. 85(2):430-444.e6.
Wang W, Wang Y, Sanidad KZ, Wang Y, Zhang J, Yang W, Sun Q, Bayram I, Song R, Yang H et al..  2025.  Oxidized Polyunsaturated Fatty Acid Promotes Colitis and Colitis-Associated Tumorigenesis in Mice.. J Crohns Colitis. 19(3)
Robinson LA, Pascual V.  2025.  Recent insights into the role of innate immunity in lupus.. Hum Mol Genet.
Nehar-Belaid D, Mejias A, Xu Z, Marches R, Yerrabelli R, Chen G, Mertz S, Ye F, Sánchez PJ, Tsang JS et al..  2025.  SARS-CoV-2 induced immune perturbations in infants vary with disease severity and differ from adults' responses.. Nat Commun. 16(1):4562.
Choi I, Kim K-A, Kim SCheol, Park D, Nam KTaek, Cha JHyung, Baek S, Cha J, Jo H-Y, Jung M et al..  2025.  Secretory IgA dysfunction underlies poor prognosis in Fusobacterium-infected colorectal cancer.. Gut Microbes. 17(1):2528428.
Sun J, Jo G, Troxell CA, Fu Y, Hoezl R, Lv H, Abozeid HH, Teo QWen, Pholcharee T, McGrath JJC et al..  2025.  A single residue change only differing by an atomic group can drive imprinting to influenza.. Res Sq.
Nehar-Belaid D, Thibodeau A, Eroglu A, Marches R, Eryilmaz G, Unutmaz D, Verschoor CP, Gu J, Balaji U, Mejias A et al..  2025.  Single-cell map of the healthy human immune system across the lifespan reveals unique infant immune signatures.. bioRxiv.
Balasubramanian P, Balaji U, Santos MSilva, Baisch J, Smitherman C, Walters L, Sparagana P, Nassi L, Stewart K, Fuller J et al..  2025.  Single-cell RNA profiling of blood CD4+ T cells identifies distinct helper and dysfunctional regulatory clusters in children with SLE.. Nat Immunol.
Tsou P-S, Ali RA, Lu C, Sule G, Carmona-Rivera C, Lucotti S, Ikari Y, Wu Q, Campbell PL, Gurrea-Rubio M et al..  2025.  Soluble CD13 is a potential mediator of neutrophil-induced thrombogenic inflammation in SARS-CoV-2 infection.. JCI Insight. 10(9)
Lin T-H, Lee C-CDavid, Fernández-Quintero ML, Ferguson JA, Han J, Zhu X, Yu W, Guthmiller JJ, Krammer F, Wilson PC et al..  2025.  Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes.. Nat Commun. 16(1):1268.