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Gale and Ira Drukier Institute for Children's Health

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Mary Teruel, PhD

LABORATORY OF DIABETES AND OBESITY SIGNALING: Terminal cell differentiation is crucial for developing, maintaining, and regenerating tissues in all multi-cellular organisms. The overarching focus of the Teruel Lab is to understand how to control terminal differentiation in order to maintain a dynamic balance between progenitor and differentiated cells that ensures healthy tissue development and prevents disease. To tackle this problem, my lab developed a platform to understand adipogenesis (fat cell differentiation) and other differentiation processes based on live and fixed-cell microscopy and analysis tools to simultaneously monitor and perturb signaling, cell cycle, and differentiation processes in thousands of single cells. To validate the relevance of our discoveries, we combine in vitro cell culture, organoid, and in vivo mouse models.

https://www.teruellab.org/

Weill Cornell Medicine
Gale and Ira Drukier Institute for Children's Health
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